:root{--bg: #f3f7f8;--bg-elevated: #ffffff;--bg-muted: #e8f0f2;--bg-soft: #dce9ec;--ink: #12262c;--ink-secondary: #3d5a63;--ink-muted: #6b858e;--line: #c5d6db;--line-strong: #9bb4bc;--accent: #0f766e;--accent-strong: #0b5f59;--accent-soft: #d5f0ed;--navy: #1a3a4a;--warn: #b45309;--danger: #b91c1c;--danger-soft: #fde8e8;--ok: #047857;--shadow: 0 10px 30px rgba(18, 38, 44, .08);--radius: 14px;--radius-sm: 10px;--font-display: "Outfit", "IBM Plex Sans JP", sans-serif;--font-body: "IBM Plex Sans JP", "Hiragino Sans", "Noto Sans JP", sans-serif;--header-h: 56px;--safe-top: env(safe-area-inset-top, 0px);--safe-bottom: env(safe-area-inset-bottom, 0px);--safe-left: env(safe-area-inset-left, 0px);--safe-right: env(safe-area-inset-right, 0px);--header-total: calc(var(--header-h) + var(--safe-top));--app-vh: 100vh;--app-vh: 100dvh;--space-1: 4px;--space-2: 8px;--space-3: 12px;--space-4: 16px;--space-5: 24px;--space-6: 32px}*,*:before,*:after{box-sizing:border-box}html,body,#root{height:100%;height:var(--app-vh);max-height:var(--app-vh);overflow:hidden}body{margin:0;color:var(--ink);background:radial-gradient(1200px 600px at 10% -10%,#d9f3ef 0%,transparent 55%),radial-gradient(900px 500px at 100% 0%,#d7e6f0 0%,transparent 50%),var(--bg);font-family:var(--font-body);font-size:15px;line-height:1.55;-webkit-font-smoothing:antialiased;-webkit-tap-highlight-color:transparent;overscroll-behavior:none}button,input,select{font:inherit}button{cursor:pointer}a{color:inherit;text-decoration:none}.app-shell{min-height:100%;height:var(--app-vh);max-height:var(--app-vh);display:flex;flex-direction:column;overflow:hidden}.app-header{height:var(--header-total);box-sizing:border-box;display:flex;align-items:center;justify-content:space-between;gap:var(--space-3);padding:var(--safe-top) max(var(--space-5),var(--safe-right)) 0 max(var(--space-5),var(--safe-left));border-bottom:1px solid var(--line);background:#ffffffd1;-webkit-backdrop-filter:blur(10px);backdrop-filter:blur(10px);position:sticky;top:0;z-index:20;flex-shrink:0}.brand-mark{display:flex;align-items:baseline;gap:var(--space-2);font-family:var(--font-display);letter-spacing:.02em;min-width:0;flex:1}.brand-mark strong{font-size:1.15rem;color:var(--navy);flex-shrink:0}.brand-mark span{font-size:.78rem;color:var(--ink-muted);font-weight:500;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;min-width:0}.nav-back{border:1px solid var(--line);background:var(--bg-elevated);color:var(--ink-secondary);border-radius:999px;padding:6px 14px;transition:background .15s ease,border-color .15s ease;flex-shrink:0}.nav-back:hover{background:var(--bg-muted);border-color:var(--line-strong)}.app-main{flex:1;min-height:0;overflow:hidden;overscroll-behavior:contain}.scroll-y{overflow-x:hidden;overflow-y:auto;-webkit-overflow-scrolling:touch;overscroll-behavior-y:contain;touch-action:pan-y;min-height:0}.home{height:100%;overflow-x:hidden;overflow-y:auto;-webkit-overflow-scrolling:touch;overscroll-behavior-y:contain;touch-action:pan-y;display:grid;grid-template-rows:auto 1fr auto;padding:var(--space-6) var(--space-5) calc(var(--space-5) + var(--safe-bottom));gap:var(--space-5)}.home-hero{max-width:720px;animation:rise .55s ease both}.home-hero h1{margin:0;font-family:var(--font-display);font-size:clamp(2.4rem,5vw,3.4rem);line-height:1.05;letter-spacing:-.02em;color:var(--navy)}.home-hero p{margin:var(--space-3) 0 0;color:var(--ink-secondary);font-size:1.05rem;max-width:36rem}.pwa-hint{margin-top:var(--space-4);max-width:36rem;display:flex;flex-wrap:wrap;align-items:flex-start;justify-content:space-between;gap:10px 12px;padding:12px 14px;border:1px solid color-mix(in srgb,var(--accent) 35%,var(--line));border-radius:var(--radius-sm);background:color-mix(in srgb,var(--accent-soft) 55%,white)}.pwa-hint-body{flex:1;min-width:12rem}.pwa-hint-body strong{display:block;color:var(--accent-strong);font-size:.92rem}.pwa-hint-body p{margin:4px 0 0;font-size:.85rem;color:var(--ink-secondary);line-height:1.45}.pwa-hint-actions{display:inline-flex;gap:8px;flex-shrink:0}.pwa-hint-install,.pwa-hint-dismiss{border-radius:999px;min-height:36px;padding:6px 12px;font-size:.82rem;font-weight:650}.pwa-hint-install{border:1px solid var(--accent);background:var(--accent);color:#fff}.pwa-hint-dismiss{border:1px solid var(--line);background:var(--bg-elevated);color:var(--ink-secondary)}.mode-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:var(--space-4);align-content:start;max-width:1100px}.mode-card{position:relative;display:flex;flex-direction:column;gap:var(--space-3);min-height:168px;padding:var(--space-5);border-radius:var(--radius);border:1px solid var(--line);background:var(--bg-elevated);box-shadow:var(--shadow);text-align:left;transition:transform .18s ease,border-color .18s ease,box-shadow .18s ease;animation:rise .55s ease both}.mode-card:nth-child(1){animation-delay:.05s}.mode-card:nth-child(2){animation-delay:.1s}.mode-card:nth-child(3){animation-delay:.15s}.mode-card:nth-child(4){animation-delay:.2s}.mode-card:nth-child(5){animation-delay:.25s}.mode-card.enabled:hover{transform:translateY(-3px);border-color:var(--accent);box-shadow:0 16px 36px #0f766e24}.mode-card:disabled,.mode-card.disabled{opacity:.62;cursor:not-allowed;box-shadow:none}.mode-card .mode-label{font-family:var(--font-display);font-size:1.2rem;font-weight:650;color:var(--navy)}.mode-card .mode-desc{color:var(--ink-secondary);font-size:.92rem;margin:0;flex:1}.mode-progress{margin:0;font-size:.78rem;font-weight:600;color:var(--accent);letter-spacing:.01em}.home-progress-foot{max-width:1100px;display:flex;justify-content:flex-end}.home-reset-progress{border:none;background:transparent;color:var(--ink-muted);font-size:.82rem;text-decoration:underline;text-underline-offset:3px;padding:4px 0}.home-reset-progress:hover{color:var(--ink-secondary)}.mode-badge{align-self:flex-start;font-size:.72rem;font-weight:600;letter-spacing:.04em;text-transform:uppercase;padding:4px 8px;border-radius:999px;background:var(--accent-soft);color:var(--accent-strong)}.mode-badge.soon{background:var(--bg-soft);color:var(--ink-muted)}.zukan{height:100%;display:grid;grid-template-columns:minmax(300px,380px) 1fr;gap:0;min-height:0}.zukan-side{display:flex;flex-direction:column;min-height:0;overflow:hidden;border-right:1px solid var(--line);background:#ffffffb8}.zukan-detail{min-height:0;overflow-x:hidden;overflow-y:auto;-webkit-overflow-scrolling:touch;overscroll-behavior-y:contain;touch-action:pan-y;background:transparent}.filter-bar{padding:var(--space-4);border-bottom:1px solid var(--line);display:flex;flex-direction:column;gap:var(--space-3)}.filter-row{display:flex;flex-wrap:wrap;gap:var(--space-2)}.filter-field{display:flex;flex-direction:column;gap:4px;flex:1;min-width:120px}.filter-field label{font-size:.72rem;font-weight:600;color:var(--ink-muted);letter-spacing:.04em}.filter-field input,.filter-field select{width:100%;border:1px solid var(--line);border-radius:var(--radius-sm);padding:8px 10px;background:var(--bg-elevated);color:var(--ink)}.filter-field input:focus,.filter-field select:focus{outline:2px solid color-mix(in srgb,var(--accent) 45%,white);border-color:var(--accent)}.chip-row{display:flex;flex-wrap:wrap;gap:6px;max-height:72px;overflow:auto}.chip{border:1px solid var(--line);background:var(--bg-elevated);color:var(--ink-secondary);border-radius:999px;padding:3px 10px;font-size:.78rem;line-height:1.4}.chip.active{background:var(--accent-soft);border-color:var(--accent);color:var(--accent-strong);font-weight:600}.chip.tag{cursor:pointer}.result-meta{font-size:.8rem;color:var(--ink-muted);padding:0 var(--space-4) var(--space-2)}.drug-list{flex:1;overflow-x:hidden;overflow-y:auto;-webkit-overflow-scrolling:touch;overscroll-behavior-y:contain;touch-action:pan-y;min-height:0;padding:0 var(--space-2) var(--space-3)}.drug-row{width:100%;display:grid;grid-template-columns:1fr auto;gap:4px 10px;text-align:left;border:1px solid transparent;background:transparent;border-radius:var(--radius-sm);padding:10px 12px;color:inherit}.drug-row:hover{background:var(--bg-muted)}.drug-row.selected{background:var(--accent-soft);border-color:color-mix(in srgb,var(--accent) 35%,white)}.drug-row .generic{font-weight:600;color:var(--navy)}.drug-row .brand{grid-column:1 / -1;font-size:.82rem;color:var(--ink-muted)}.drug-row-badges{display:inline-flex;flex-wrap:wrap;gap:4px;align-items:center;justify-content:flex-end}.kubun-badge{align-self:start;font-size:.7rem;font-weight:600;padding:2px 8px;border-radius:999px;background:var(--bg-soft);color:var(--ink-secondary);white-space:nowrap}.freq-badge{font-size:.68rem;font-weight:700;padding:2px 7px;border-radius:999px;background:color-mix(in srgb,var(--accent-soft) 85%,white);color:var(--accent-strong);border:1px solid color-mix(in srgb,var(--accent) 30%,var(--line));white-space:nowrap;font-variant-numeric:tabular-nums}.detail-panel{padding:var(--space-5);max-width:920px}.detail-empty{height:100%;display:grid;place-items:center;color:var(--ink-muted);padding:var(--space-6)}.detail-title{margin:0;font-family:var(--font-display);font-size:clamp(1.6rem,2.4vw,2.1rem);line-height:1.15;color:var(--navy)}.detail-brand{margin:6px 0 0;color:var(--ink-secondary);font-size:1.05rem}.detail-id{margin-top:4px;font-size:.8rem;color:var(--ink-muted);letter-spacing:.04em}.meta-grid{margin-top:var(--space-4);display:grid;grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:var(--space-3)}.meta-item{background:var(--bg-elevated);border:1px solid var(--line);border-radius:var(--radius-sm);padding:10px 12px}.meta-item dt{margin:0;font-size:.7rem;font-weight:600;color:var(--ink-muted);letter-spacing:.04em}.meta-item dd{margin:4px 0 0;font-weight:500;color:var(--ink);word-break:break-word}.price-block{margin-top:var(--space-4);padding:var(--space-4);border-radius:var(--radius);border:1px solid var(--line);background:var(--bg-elevated)}.price-block .price-text{margin:0 0 var(--space-3);color:var(--ink-secondary);font-size:.92rem}.score-pair{display:grid;grid-template-columns:1fr 1fr;gap:var(--space-3)}.score-block{min-width:0}.score-bar{display:grid;grid-template-columns:repeat(10,1fr);gap:4px}.score-bar span{height:10px;border-radius:999px;background:var(--bg-soft)}.score-bar.tone-price span.on{background:linear-gradient(90deg,#0f766e,#1a3a4a)}.score-bar.tone-usage span.on{background:linear-gradient(90deg,#b45309,#c2410c)}.score-label{margin-top:8px;font-size:.8rem;color:var(--ink-muted)}.score-hint{margin:var(--space-3) 0 0;font-size:.75rem;color:var(--ink-muted);line-height:1.4}@media(max-width:520px){.score-pair{grid-template-columns:1fr}}.tag-section{margin-top:var(--space-4)}.tag-section h3{margin:0 0 var(--space-2);font-size:.78rem;color:var(--ink-muted);letter-spacing:.04em}.tabs{margin-top:var(--space-5);display:flex;gap:6px;border-bottom:1px solid var(--line)}.tab{border:none;background:transparent;padding:10px 14px;color:var(--ink-muted);font-weight:600;border-bottom:2px solid transparent;margin-bottom:-1px}.tab.active{color:var(--accent-strong);border-bottom-color:var(--accent)}.tab-panel{padding:var(--space-4) 0 var(--space-6);display:flex;flex-direction:column;gap:var(--space-4)}.section-card{background:var(--bg-elevated);border:1px solid var(--line);border-radius:var(--radius);padding:var(--space-4)}.section-card h4{margin:0 0 var(--space-2);font-size:.85rem;color:var(--navy)}.section-card p,.section-card pre{margin:0;white-space:pre-wrap;font-family:inherit;color:var(--ink-secondary);font-size:.95rem}.section-card.pros h4{color:var(--ok)}.section-card.cons h4{color:var(--warn)}.section-card.side-effects h4{color:var(--danger)}.section-card.caution h4{color:var(--warn)}.section-card.contra h4{color:var(--danger)}.structure-formula-img{display:block;width:100%;max-width:360px;height:auto;margin:0 auto;background:#fff;border:1px solid var(--line);border-radius:calc(var(--radius) - 2px);padding:var(--space-3);object-fit:contain}.chip.structure-chip{background:#eef6f4;color:var(--accent-strong);border:1px solid rgba(15,118,110,.18);cursor:default}.structure-point-list{list-style:none;margin:0;padding:0;display:grid;gap:var(--space-3)}.structure-point-list li{display:grid;gap:6px;padding:var(--space-3);border-radius:calc(var(--radius) - 2px);background:var(--bg-soft);border:1px solid var(--line)}.structure-point-list li.primary{background:#0f766e0f;border-color:#0f766e38}.structure-point-tag{display:inline-flex;align-self:start;font-size:.72rem;font-weight:700;letter-spacing:.03em;color:var(--accent-strong);background:#fff;border:1px solid rgba(15,118,110,.2);border-radius:999px;padding:2px 8px}.structure-point-list p{margin:0;color:var(--ink-secondary);font-size:.95rem;line-height:1.55}.detail-hint{margin:0;font-size:.82rem;color:var(--ink-muted)}.chip.warn{background:#fff7ed;border-color:#fdba74;color:var(--warn)}.chip.danger{background:var(--danger-soft);border-color:#fca5a5;color:var(--danger)}.mobile-toggle{display:none}.loading,.error-box{padding:var(--space-6);color:var(--ink-secondary)}.error-box{color:var(--danger)}@keyframes rise{0%{opacity:0;transform:translateY(10px)}to{opacity:1;transform:translateY(0)}}@media(max-width:900px){.app-main:has(.zukan),.app-main:has(.quiz-screen),.app-main:has(.home),.app-main:has(.sit-guide){overflow-x:hidden;overflow-y:auto;-webkit-overflow-scrolling:touch;overscroll-behavior-y:contain;touch-action:pan-y}.home{height:auto;min-height:100%;overflow:visible}.zukan{grid-template-columns:1fr;height:auto;min-height:100%;overflow:visible}.zukan-side{border-right:none;max-height:none;height:auto;min-height:0;overflow:visible;background:#ffffffeb}.zukan.show-detail .zukan-side,.zukan.show-list .zukan-detail{display:none}.zukan-detail{height:auto;overflow:visible;padding-bottom:calc(var(--space-4) + var(--safe-bottom))}.filter-bar{padding:var(--space-3);gap:var(--space-2);flex-shrink:0;position:sticky;top:0;z-index:5;background:#fffffff5;-webkit-backdrop-filter:blur(8px);backdrop-filter:blur(8px)}.filter-bar.compact .filter-advanced{display:none}.filter-bar.compact .filter-advanced.open{display:flex;flex-direction:column;gap:var(--space-3);padding-top:var(--space-2);border-top:1px solid var(--line);margin-top:2px;max-height:none;overflow:visible}.filter-mobile-tools{display:flex;gap:8px;align-items:center}.filter-toggle,.filter-clear-sm{border:1px solid var(--line);background:var(--bg-elevated);color:var(--ink-secondary);border-radius:var(--radius-sm);padding:8px 12px;font-size:.85rem;font-weight:600;min-height:40px}.filter-toggle{flex:1;display:inline-flex;justify-content:space-between;align-items:center;gap:8px}.filter-toggle.open{background:var(--accent-soft);border-color:var(--accent);color:var(--accent-strong)}.filter-clear-sm{flex-shrink:0}.filter-field input,.filter-field select,.chip{min-height:40px;font-size:.9rem}.chip{padding:6px 12px}.chip-row{max-height:none}.result-meta{padding:6px var(--space-3);flex-shrink:0}.drug-list{flex:none;min-height:0;overflow:visible;padding-bottom:calc(var(--space-4) + var(--safe-bottom))}.drug-row{padding:12px var(--space-3);gap:6px;align-items:flex-start}.drug-row .generic{font-size:1rem}.detail-panel{padding:var(--space-4) var(--space-3) calc(var(--space-6) + var(--safe-bottom))}.detail-title{font-size:1.35rem;line-height:1.3}.meta-grid{grid-template-columns:1fr 1fr;gap:8px}.tabs{position:sticky;top:0;z-index:2;background:color-mix(in srgb,var(--bg, #fff) 92%,transparent);-webkit-backdrop-filter:blur(8px);backdrop-filter:blur(8px);padding:4px 0;overflow-x:auto;overflow-y:hidden;flex-wrap:nowrap;-webkit-overflow-scrolling:touch;touch-action:pan-x;overscroll-behavior-x:contain}.tab{flex:0 0 auto;min-height:40px;padding:8px 14px;white-space:nowrap}.mobile-toggle{display:inline-flex;min-height:40px;margin-bottom:var(--space-3)}.home{padding:var(--space-5) var(--space-4) calc(var(--space-5) + var(--safe-bottom));grid-template-rows:auto auto}.home-hero h1{font-size:clamp(1.85rem,7vw,2.5rem)}.home-hero p{font-size:.95rem}.mode-grid{grid-template-columns:1fr;gap:var(--space-3)}.mode-card{min-height:0;padding:var(--space-4)}.app-header{padding-left:max(var(--space-3),var(--safe-left));padding-right:max(var(--space-3),var(--safe-right))}.nav-back{padding:6px 12px;font-size:.85rem}}@media(min-width:901px){.filter-mobile-tools{display:none}.filter-bar.compact .filter-advanced{display:flex;flex-direction:column;gap:var(--space-3)}}.quiz-screen{height:100%;max-height:100%;overflow:hidden;padding:var(--space-4) var(--space-5);display:flex;flex-direction:column;box-sizing:border-box}.quiz-center{margin:auto;color:var(--ink-secondary);text-align:center}.quiz-setup,.quiz-play,.quiz-result{flex:1;min-height:0;display:flex;flex-direction:column;gap:var(--space-3);max-width:720px;width:100%;margin:0 auto}.quiz-head h2,.quiz-result h2{margin:0;font-family:var(--font-display);color:var(--navy);font-size:1.6rem}.quiz-head p{margin:4px 0 0;color:var(--ink-secondary);font-size:.92rem}.quiz-block{background:var(--bg-elevated);border:1px solid var(--line);border-radius:var(--radius);padding:var(--space-3) var(--space-4);flex-shrink:0}.quiz-block-grow{flex:1;min-height:0;display:flex;flex-direction:column;gap:var(--space-2)}.quiz-block h3{margin:0 0 var(--space-2);font-size:.78rem;letter-spacing:.04em;color:var(--ink-muted)}.quiz-seg{display:grid;grid-template-columns:repeat(3,1fr);gap:6px}.quiz-seg:has(.quiz-seg-btn:nth-child(2):last-child){grid-template-columns:repeat(2,1fr)}.quiz-seg-btn{border:1px solid var(--line);background:var(--bg);border-radius:var(--radius-sm);padding:10px 8px;font-weight:600;color:var(--ink-secondary)}.quiz-seg-btn.active{background:var(--accent-soft);border-color:var(--accent);color:var(--accent-strong)}.quiz-chips{display:flex;flex-wrap:wrap;gap:6px;overflow:auto;-webkit-overflow-scrolling:touch;max-height:100%;padding-bottom:2px}.quiz-meta{margin:0;font-size:.82rem;color:var(--ink-muted)}.quiz-actions{display:flex;gap:var(--space-2);flex-shrink:0}.quiz-actions.row{flex-wrap:wrap;justify-content:center}.quiz-btn{border:1px solid var(--line);background:var(--bg-elevated);color:var(--ink);border-radius:999px;padding:10px 18px;font-weight:600}.quiz-btn.primary{background:var(--accent);border-color:var(--accent);color:#fff}.quiz-btn.primary:disabled{opacity:.45;cursor:not-allowed}.quiz-btn.primary:hover:not(:disabled){background:var(--accent-strong)}.quiz-progress{display:flex;justify-content:space-between;font-size:.85rem;font-weight:600;color:var(--ink-secondary);flex-shrink:0}.quiz-prompt{display:flex;align-items:center;gap:var(--space-2);flex-shrink:0}.quiz-ask{font-family:var(--font-display);font-size:1.25rem;font-weight:650;color:var(--navy)}.quiz-hint-card{flex:1;min-height:0;overflow:hidden;background:var(--bg-elevated);border:1px solid var(--line);border-radius:var(--radius);padding:var(--space-4);display:flex;flex-direction:column;gap:var(--space-2)}.quiz-hint-meta{display:flex;flex-wrap:wrap;gap:8px;align-items:baseline;flex-shrink:0}.quiz-hint-meta 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.sit-dose-label{color:var(--sit-maintain)}.sit-guide-drug-link{border:none;background:transparent;color:var(--tone-ink);font-weight:800;font-size:inherit;padding:0;min-height:0;text-decoration:underline;text-decoration-thickness:2px;text-underline-offset:3px;cursor:pointer}.sit-guide-drug-name{font-weight:800;color:var(--navy)}.sit-guide-cell-pre{margin:0;font-family:inherit;font-size:.84rem;white-space:pre-wrap;overflow-wrap:anywhere;word-break:break-word;color:var(--ink);font-weight:550}.sit-guide-tips{margin:0;color:var(--ink-secondary);overflow-wrap:anywhere;word-break:break-word;font-size:.84rem}.sit-guide-cards{display:none}@media(max-width:900px){.sit-guide{display:flex;flex-direction:column;height:auto;min-height:100%;overflow:visible}.sit-guide-side{border-right:none;border-bottom:1px solid 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